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Gene Expression Data
Assay Details
Assay
Reference: J:343078 Diniz F, et al., Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance. Nat Commun. 2023 Nov 25;14(1):7733
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7567407
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Antibody: anti-Wnt4 (AF475)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 8a: postnatal day 0; Aclytm1.1Welk/Acly+ (more )
Note: Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - DBA.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted 8a Authors report expression in PTA and RV structures.
Specimen 8b: postnatal day 0; Aclytm1.1Welk/Acly+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - DBA.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted 8b Expansion of expression towards cap mesenchyme.
Specimen 8c: postnatal day 0; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - DBA.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted 8c Expression expanded compared to wild type.
Specimen 8g: embryonic day 16.5; Aclytm1.1Welk/Acly+ (more )
Note: Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - cytokeratin.
Structure Level Pattern Image Note
TS24: metanephros Present 8g
Specimen 8h: embryonic day 16.5; Aclytm1.1Welk/Acly+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - cytokeratin.
Structure Level Pattern Image Note
TS24: metanephros Present 8h
Specimen 8i: embryonic day 16.5; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - cytokeratin.
Structure Level Pattern Image Note
TS24: metanephros Present 8i
Specimen 8j: embryonic day 14.5; Aclytm1.1Welk/Acly+ (more )
Note: Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - cytokeratin.
Structure Level Pattern Image Note
TS22: metanephros Present 8j
Specimen 8k: embryonic day 14.5; Aclytm1.1Welk/Acly+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - cytokeratin.
Structure Level Pattern Image Note
TS22: metanephros Present 8k
Specimen 8l: embryonic day 14.5; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: white - Wnt4; red - Six2 (assay MGI:7567406); green - cytokeratin.
Structure Level Pattern Image Note
TS22: metanephros Present 8l
Specimen S10c/e: postnatal day 0; Aclytm1.1Welk/Acly+ (more )
Note: Multi-labeled: cyan - Wnt4; red - Six2 (assay MGI:7567406); green - DBA; blue - Hoechst.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted S10e , S10c Expression in nascent nephrons and differentiating nephron progenitor cells.
Specimen S10h/j: postnatal day 0; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Multi-labeled: cyan - Wnt4; red - Six2 (assay MGI:7567406); green - DBA; blue - Hoechst.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted S10j , S10h Expression expanded compared to wild type.
Specimen S10m/o: postnatal day 0; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Multi-labeled: cyan - Wnt4; red - Six2 (assay MGI:7567406); green - DBA; blue - Hoechst.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted S10m , S10o Expression expanded compared to wild type.
Specimen S10r/t: postnatal day 0; Aclytm1.1Welk/Acly+ (more )
Note: Multi-labeled: cyan - Wnt4; red - Six2 (assay MGI:7567406); green - DBA; blue - Hoechst.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted S10t , S10r Authors report expression in PTA and RV structures.
Specimen S10w/y: postnatal day 0; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Multi-labeled: cyan - Wnt4; red - Six2 (assay MGI:7567406); green - DBA; blue - Hoechst.
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted S10y , S10w Expression expanded compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory