Tg(tetO/CMV-MANF)#Mlin
Transgene Detail
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| Symbol: |
Tg(tetO/CMV-MANF)#Mlin |
| Name: |
transgene insertion, Maria Lindahl |
| MGI ID: |
MGI:7565868 |
| Synonyms: |
TET-MANF Tg |
| Transgene: |
Tg(tetO/CMV-MANF)#Mlin Location: unknown
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| Alliance: |
Tg(tetO/CMV-MANF)#Mlin page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Tg(tetO/CMV-MANF)#Mlin expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
MANF (7873) |
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Mutation details: The full-length human MANF cDNA was inserted between seven direct repeats of the tet-operator sequence/CMV promoter and the mouse protamine 1 polyA and intron sequence. The pound symbol (#) is used when line is not specified and/or lines are pooled.
(J:343282)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:343282 Kim Y, et al., MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice. Nat Commun. 2023 Oct 14;14(1):6493 |
| All: |
1 reference(s) |
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Analysis Tools
