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Gene Expression Data
Assay Details
Assay
Reference: J:343157 Snippert HJ, et al., Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine. Gastroenterology. 2009 Jun;136(7):2187-2194.e1
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7564464
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Reporter: GFP
Direct Detection
Results
Specimen 1A: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Note: Double labeled: green - Lgr5; red - To-Pro-3.
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 1A Expression is seen in 6-8 cells at the bottom of the crypts, intermingled with differentiated Paneth cells.
Specimen 2D: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Note: Double labeled: green - Lgr5 reporter; blue - Prom1 (assay MGI:7564467).
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 2D Expression is seen in the bottom of the crypts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory