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Gene Expression Data
Assay Details
Assay
Reference: J:128304 Petrou P, et al., Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa. Matrix Biol. 2007 Oct;26(8):652-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7564079
Gene symbol: Frem1
Gene name: Fras1 related extracellular matrix protein 1
Antibody: anti-Frem1
Detection system: Secondary antibody coupled to colloidal gold
Assay notes: Immunoelectron microscopy.
Results
Specimen 5D: embryonic day 14.5 (more )
Note: Fixative was 4% paraformaldehyde, 0.05% glutaraldehyde and 15% saturated picric acid.
Structure Level Pattern Image Note
TS22: back skin Present Regionally restricted 5D Expression is as a clustered arrangement underneath the lamina densa in two different parts of the skin. Immunogold clusters are distributed along the length of the anchoring-like fibrils that emanate from the lamina densa and extend to cells of the connective tissue. There are also localizatiosn in the lamina lucida. Absent in interstitial collagen fibers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory