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Gene Expression Data
Assay Details
Assay
Reference: J:128304 Petrou P, et al., Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa. Matrix Biol. 2007 Oct;26(8):652-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7564020
Gene symbol: Frem2
Gene name: Fras1 related extracellular matrix protein 2
Antibody: anti-Frem2
Detection system: Biotinylated secondary antibody/[Strept]avidin
Assay notes: A Tyramide signal amplification step was used.
Results
Specimen 1C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Present Regionally restricted 1C Expression is in the epithelial basement membrane of the skin.
TS22: skin Present Regionally restricted 1C Expression is in the epithelial basement membrane of the skin.

Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Present Regionally restricted 1H Expression is in the epithelial basement membrane of the developing airways and visceral pleura in the lung.
TS22: lung Present Regionally restricted 1H Expression is in the epithelial basement membrane of the developing airways and visceral pleura in the lung.
TS22: visceral pleura Present Regionally restricted 1H Expression is in the epithelial basement membrane of the developing airways and visceral pleura in the lung.

Specimen 1M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Present Regionally restricted 1M Expression is in the epithelial basement membrane of the kidney.
TS22: metanephros Present Regionally restricted 1M Expression is in the epithelial basement membrane of the kidney.

Specimen 2D: embryonic day 14.5; Fras1tm1Chpk/Fras1tm1Chpk (more )
Structure Level Pattern Image Note
TS22: epidermis Present 2D In this mutant there is an intracellular accumulation of protein in epithelial cells.
TS22: basement membrane of epithelium Absent 2D

Specimen 2E: embryonic day 14.5; Fras1tm1Chpk/Fras1tm1Chpk (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present Regionally restricted 2E In this mutant there is an intracellular accumulation of protein in epithelial cells.
TS22: basement membrane of epithelium Absent 2E

Specimen 2F: embryonic day 14.5; Fras1tm1Chpk/Fras1tm1Chpk (more )
Structure Level Pattern Image Note
TS22: metanephros epithelium Trace Regionally restricted 2F In this mutant there is an intracellular accumulation of protein in epithelial cells.
TS22: basement membrane of epithelium Absent 2F Expression is absent in the epithelial basement membrane of the kidney.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory