About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:203073 Cesca F, et al., Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems. Cell Death Differ. 2012 Feb;19(2):194-208
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7562501
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2B +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: telencephalon subventricular zone Ambiguous 2Ba , 2Bb

Specimen 2B Kidins220-/-: embryonic day 18.5; Kidins220tm1.2Fces/Kidins220tm1.2Fces (more )
Structure Level Pattern Image Note
TS26: telencephalon subventricular zone Present 2Bd , 2Bc
TS26: telencephalon Present Regionally restricted 2Bc , 2Bd Expression was detected in the neuroepithelium and subventricular zone.

Specimen 2C +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Ambiguous 2Cb , 2Ca
TS26: hippocampal formation Ambiguous 2Cc , 2Ca
TS26: caudate-putamen Ambiguous 2Ca , 2Cd

Specimen 2C Kidins220-/-: embryonic day 18.5; Kidins220tm1.2Fces/Kidins220tm1.2Fces (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present 2Cf , 2Ce
TS26: hippocampal formation Present Regionally restricted 2Ce , 2Cg Expression was detected in the dorsal subiculum of the hippocampus.
TS26: caudate-putamen Present 2Ch , 2Ce

Specimen 2Da +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: medial thalamic group Ambiguous 2Da , 2Db
TS26: ventral posterior medial thalamic nucleus Ambiguous 2Da , 2Db

Specimen 2Dc +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: nucleus reuniens Ambiguous 2Dc , 2Dd

Specimen 2De Kidins220-/-: embryonic day 18.5; Kidins220tm1.2Fces/Kidins220tm1.2Fces (more )
Structure Level Pattern Image Note
TS26: medial thalamic group Present 2De , 2Df
TS26: ventral posterior medial thalamic nucleus Present 2De , 2Df

Specimen 2Dg Kidins220-/-: embryonic day 18.5; Kidins220tm1.2Fces/Kidins220tm1.2Fces (more )
Structure Level Pattern Image Note
TS26: nucleus reuniens Present 2Dg , 2Dh

Specimen 3A +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 3Aa +/+

Specimen 3A Kidins220-/-: embryonic day 13.5; Kidins220tm1.2Fces/Kidins220tm1.2Fces (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 3Aa Kidins220-/- The number of immunoreactive cells from thoracic and lumbar ganglia was significantly increased in the mutant tissue, compared with the wild type.

Specimen 3B +/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: glossopharyngeal ganglion Present 3Ba +/+
TS22: vestibular ganglion Present 3Ba +/+

Specimen 3B Kidins220-/-: embryonic day 14.5; Kidins220tm1.2Fces/Kidins220tm1.2Fces (more )
Structure Level Pattern Image Note
TS22: glossopharyngeal ganglion Present 3Ba Kidins220-/- The number of immunoreactive cells was significantly increased in the mutant tissue, compared with the wild type.
TS22: vestibular ganglion Present 3Ba Kidins220-/- The number of immunoreactive cells was significantly increased in the mutant tissue, compared with the wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/31/2026
MGI 6.24
The Jackson Laboratory