Tg(Prnp-Ldlr)EHol
Transgene Detail
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| Symbol: |
Tg(Prnp-Ldlr)EHol |
| Name: |
transgene insertion E, David M Holtzman |
| MGI ID: |
MGI:7548807 |
| Transgene: |
Tg(Prnp-Ldlr)EHol Location: unknown
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| Alliance: |
Tg(Prnp-Ldlr)EHol page
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| Strain of Origin: |
C57BL/6 x CBA
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Prnp-Ldlr)EHol expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Ldlr (MGI:96765) |
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Tg(Prnp-Ldlr)EHol expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Prnp (MGI:97769) |
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Mutation details: A mouse prnp promoter drives expression of a mouse Ldlr cDNA. Two lines were generated, a high-expressing B line and low-expressing E line.
(J:155809)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:155809 Kim J, et al., Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron. 2009 Dec 10;64(5):632-44 |
| All: |
1 reference(s) |
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Analysis Tools
