Summary | Mutation origin | Mutation description | Recombinase activity | Tumor data | Find Mice (IMSR) | References

Symbol:	Msi2tm1.1(cre/ERT2)Reya
Name:	musashi RNA-binding protein 2; targeted mutation 1.1, Tannishtha Reya
MGI ID:	MGI:7548734
Synonyms:	Msi2CreERT2
Gene:	Msi2  Location: Chr11:88230208-88609197 bp, - strand  Genetic Position: Chr11, 52.4 cM, cytoband B5-C
Alliance:	Msi2tm1.1(cre/ERT2)Reya page

Germline Transmission:	Earliest citation of germline transmission: J:342146
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Msi2tm1.1(cre/ERT2)Reya expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Msi2 (MGI:1923876)   Mutation details: A CreERT2-cassette was integrated into the start codon of the Msi2 locus exon1 via homologous recombination in ES cells. (J:342146)

Activity:	Tissue activity of this recombinase allele
Driver:	Msi2 (mouse) Summary of all recombinase alleles driven by Msi2. Comparative matrix view of recombinase activities Alliance mouse Msi2 gene page

List all tumor models in MMHCdb carrying Msi2tm1.1(cre/ERT2)Reya

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msi2 Mutation:	781 strains or lines available

Original:	J:342146 Rajbhandari N, et al., Single-cell mapping identifies MSI(+) cells as a common origin for diverse subtypes of pancreatic cancer. Cancer Cell. 2023 Sep 25;
All:	1 reference(s)