Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tas2r143-cre/ERT2)#Soff
Name:	transgene insertion, Stefan Offermanns
MGI ID:	MGI:7548525
Synonyms:	Tas2r143-CreERT2
Transgene:	Tg(Tas2r143-cre/ERT2)#Soff  Location: unknown
Alliance:	Tg(Tas2r143-cre/ERT2)#Soff page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Tas2r143-cre/ERT2)#Soff expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tas2r143 (MGI:2681310)   Mutation details: The genomic sequence between the start codon of the Tas2r143 gene and the stop codon of the Tas2r126 gene (35.2 kb) on the BAC clone RP23-316O11 containing the Tas2r143 promoter was replaced by a cassette carrying the CreERT2 cDNA followed by a polyadenylation (pA) signal. Three lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:341916)

Activity:	Tissue activity of this recombinase allele
Driver:	Tas2r143 (mouse) Summary of all recombinase alleles driven by Tas2r143. Comparative matrix view of recombinase activities Alliance mouse Tas2r143 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:341916 Liu S, et al., Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues. Front Physiol. 2017;8:849
All:	1 reference(s)