Cux1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:342123 Sterling NA, et al., P53 independent pathogenic mechanisms contribute to BubR1 microcephaly. Front Cell Dev Biol. 2023;11:1282182
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7548383
Gene symbol:	Cux1
Gene name:	cut-like homeobox 1

Antibody:	anti-CUX1 (11733-1-AP)
Detection system:	Secondary antibody

Results

7F WT ©

Specimen 7F CUX1 WT: postnatal day 21 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: cerebral cortex	neuron	Present		7F WT	Expression in late-born neurons.

7F Trp53 cKO ©

Specimen 7F CUX1 Trp53 cKO: postnatal day 21; Emx1^tm1(cre)Krj/Emx1⁺, Trp53^tm1Brn/Trp53^tm1Brn (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		7F Trp53 cKO	Expression not altered compared to wild type.

7F BubR1 cKO ©

Specimen 7F CUX1 BubR1 cKO: postnatal day 21; Bub1b^tm1Jvd/Bub1b^tm1Jvd, Emx1^tm1(cre)Krj/Emx1⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Weak		7F BubR1 cKO	Expression signficantly reduced compared to wild type.

7F dcKO ©

Specimen 7F CUX1 dcKO: postnatal day 21; Bub1b^tm1Jvd/Bub1b^tm1Jvd, Emx1^tm1(cre)Krj/Emx1⁺, Trp53^tm1Brn/Trp53^tm1Brn (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Weak		7F dcKO	Expression minimally improved compared to BubR1 cKO.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23