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Gene Expression Data
Assay Details
Assay
Reference: J:231945 Dina C, et al., Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nat Genet. 2015 Oct;47(10):1206-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7547101
Gene symbol: Igfbp5
Gene name: insulin-like growth factor binding protein 5
Antibody: anti-Igfbp5
Detection system: Secondary antibody
Results
Specimen S2 E13.5: embryonic day 13.5 (more )
Note: Double labeled: red - Igfbp5; green - MF20 (sarcomeric myosin-myocytes).
Structure Level Pattern Image Note
TS21: mitral valve Absent S2_E13.5 right , S2_E13.5 left Only faint nonspecific staining was seen.
TS21: interatrial septum Present S2_E13.5 left
TS21: left atrium cardiac muscle Present S2_E13.5 left
TS21: right atrium cardiac muscle Present S2_E13.5 left
Specimen S2 E17.5: embryonic day 17.5 (more )
Note: Double labeled: red - Igfbp5; green - MF20 (sarcomeric myosin-myocytes).
Structure Level Pattern Image Note
TS25: mitral valve leaflet Absent S2_E17.5 left , S2_E17.5 right Only faint nonspecific staining was seen.
TS25: interatrial septum Present S2_E17.5 left
TS25: left atrium cardiac muscle Present S2_E17.5 left
TS25: right atrium cardiac muscle Present S2_E17.5 left
Specimen S2 9 months: postnatal month 9 (more )
Note: Double labeled: red - Igfbp5; green - MF20 (sarcomeric myosin-myocytes).
Structure Level Pattern Image Note
TS28: mitral valve Absent S2_Adult right , S2_Adult left Only faint nonspecific staining was seen.
TS28: coronary artery Present Regionally restricted S2_Adult left Expressed in the coronary endothelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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