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Gene Expression Data
Assay Details
Assay
Reference: J:81418 Wang L, et al., Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):703-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7547094
Gene symbol: Nes
Gene name: nestin
Antibody: Rat-401 (MAB353)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6A: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex radial glial cell Present 6A , 6C Expression is in radila glial cells in an approximately radial pattern across the thickness of the cortex.

Specimen 6B: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex radial glial cell Present 6D , 6B In this mutant the radial scaffold formed by processes of radial glia are truncated and appear as many short fragments with more abundant end feet compared to wild-type.
TS26: neocortex Present 6B , 6D In this mutant the radial glial fibers formed more abundant end feet in the neurons in layer I compared to wild-type.

Specimen 6E: embryonic day 18.5; Esr2tm1Unc/Esr2tm1Unc (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex radial glial cell Present 6E In this mutant the radial scaffold formed by processes of radial glia are truncated and appear as many short fragments with more abundant end feet compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory