Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Nlrp14em2(cre/ERT2)Qys
Name:	NLR family, pyrin domain containing 14; endonuclease-mediated mutation 2, Qing-Yuan Sun
MGI ID:	MGI:7546832
Gene:	Nlrp14  Location: Chr7:106766197-106797309 bp, + strand  Genetic Position: Chr7, 56.1 cM
Alliance:	Nlrp14em2(cre/ERT2)Qys page

Strain of Origin:

C57BL/6

Allele Type:    Endonuclease-mediated (Epitope tag, Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Nlrp14em2(cre/ERT2)Qys expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nlrp14 (MGI:1924108)   Mutation details: Using CRISPR/Cas9, a 3xflag, IRES-Myc-EGFP-PP2A-3xHA-iCreERT2 sequences were inserted before the stop codon of Nlrp14 CDS. (J:341543)

Activity:	Tissue activity of this recombinase allele
Driver:	Nlrp14 (mouse) Summary of all recombinase alleles driven by Nlrp14. Alliance mouse Nlrp14 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nlrp14 Mutation:	44 strains or lines available

Original:	J:341543 Meng TG, et al., NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition. Adv Sci (Weinh). 2023 Sep;10(27):e2301940
All:	1 reference(s)