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Gene Expression Data
Assay Details
Assay
Reference: J:340875 Zhou Z, et al., Fance deficiency inhibits primordial germ cell proliferation associated with transcription-replication conflicts accumulate and DNA repair defects. J Ovarian Res. 2023 Aug 10;16(1):160
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7545025
Gene symbol: Blm
Gene name: Bloom syndrome, RecQ like helicase
Antibody: anti-BLM (PA5-27384)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 8A E11.5 +/+: embryonic day 11.5 (more )
Note: Double labeled: red - Blm; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 8A E11.5 +/+ left , 8A E11.5 +/+ right
Specimen 8A E11.5 -/-: embryonic day 11.5; FanceTg(Tyr)2364E-2a2Ove/FanceTg(Tyr)2364E-2a2Ove (more )
Note: Double labeled: red - Blm; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 8A E11.5 -/- right , 8A E11.5 -/- left The proportion of Blm positive cells was significantly decreased compared with the wild-type (quantified in Fig 8B).
Specimen 8A E12.5 +/+: embryonic day 12.5 (more )
Note: Double labeled: red - Blm; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 8A E12.5 +/+ right , 8A E12.5 +/+ left
Specimen 8A E12.5 -/-: embryonic day 12.5; FanceTg(Tyr)2364E-2a2Ove/FanceTg(Tyr)2364E-2a2Ove (more )
Note: Double labeled: red - Blm; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 8A E12.5 -/- left , 8A E12.5 -/- right The proportion of Blm positive cells was significantly decreased compared with the wild-type (quantified in Fig 8B).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory