About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:340875 Zhou Z, et al., Fance deficiency inhibits primordial germ cell proliferation associated with transcription-replication conflicts accumulate and DNA repair defects. J Ovarian Res. 2023 Aug 10;16(1):160
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7545022
Gene symbol: Fancd2
Gene name: Fanconi anemia, complementation group D2
Antibody: anti-FANCD2 (NB100-182)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 7A E11.5 +/+: embryonic day 11.5 (more )
Note: Double labeled: red - Fancd2; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 7A E11.5 +/+ left , 7A E11.5 +/+ right
Specimen 7A E11.5 -/-: embryonic day 11.5; FanceTg(Tyr)2364E-2a2Ove/FanceTg(Tyr)2364E-2a2Ove (more )
Note: Double labeled: red - Fancd2; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 7A E11.5 -/- right , 7A E11.5 -/- left The proportion of Fancd2 positive cells was significantly decreased compared with the wild-type (quantified in Fig 7B).
Specimen 7A E12.5 +/+: embryonic day 12.5 (more )
Note: Double labeled: red - Fancd2; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 7A E12.5 +/+ left , 7A E12.5 +/+ right
Specimen 7A E12.5 -/-: embryonic day 12.5; FanceTg(Tyr)2364E-2a2Ove/FanceTg(Tyr)2364E-2a2Ove (more )
Note: Double labeled: red - Fancd2; green - Fut4 (assay MGI:7544998).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 7A E12.5 -/- left , 7A E12.5 -/- right The proportion of Fancd2 positive cells was significantly decreased compared with the wild-type (quantified in Fig 7B).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory