Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:341657
Park J, et al., Msx1 Heterozygosity in Mice Enhances Susceptibility to Phenytoin-Induced Hypoxic Stress Causing Cleft Palate. Cleft Palate Craniofac J. 2021 Jun;58(6):697-706
|
|
Assay type:
|
In situ reporter (knock in)
|
|
MGI Accession ID:
|
MGI:7544992
|
|
Gene symbol:
|
Msx1
|
|
Gene name:
|
msh homeobox 1
|
|
Reporter:
|
lacZ
|
|
|
Direct Detection
|
|
|
Results
|
Specimen
S2B:
(close  )
|
Genetic Background:
|
involves: C57BL/6
|
|
Mutant Allele(s):
|
Msx1tm1b(KOMP)Wtsi/Msx1+
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: axial skeleton |
Present |
|
S2B
|
Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
|
| TS20: face |
Present |
|
S2B
|
Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
|
| TS20: forelimb |
Present |
|
S2B
|
Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
|
| TS20: hindlimb |
Present |
|
S2B
|
Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
|
| TS20: inner ear |
Present |
|
S2B
|
Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
|
Specimen
S2G:
(close )
|
Genetic Background:
|
involves: C57BL/6
|
|
Mutant Allele(s):
|
Msx1tm1b(KOMP)Wtsi/Msx1+
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: palatal shelf |
Strong |
Regionally restricted |
S2G
|
Intense expression in anterior part of palate.
|
Specimen
S2H:
(close )
|
Genetic Background:
|
involves: C57BL/6
|
|
Mutant Allele(s):
|
Msx1tm1b(KOMP)Wtsi/Msx1+
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: palatal shelf |
Strong |
Regionally restricted |
S2H
|
Intense expression in anterior part of palate.
|
|
Analysis Tools
)
