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Gene Expression Data
Assay Details
Assay
Reference: J:314358 Liu S, et al., Neural basis of opioid-induced respiratory depression and its rescue. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2022134118
Assay type: RNA in situ
MGI Accession ID: MGI:7543881
Gene symbol: Oprm1
Gene name: opioid receptor, mu 1
Probe: Mm-Oprm1 (315841)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay.
Results
Specimen S1A: postnatal adult; Oprm1tm1.1(cre/GFP)Rpa/Oprm1+ (more )
Note: Double labeled: green - Oprm1 RNA; red - Oprm1 reporter (assay MGI:7543579).
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S1A Oprm1 , S1A Merge Expression is seen in the lateral parabrachial nucleus (PBL).
Specimen S1B: postnatal adult (more )
Note: Triple labeled: gray - Oprm1; red - Slc17a6 (assay MGI:7543885); teal - Slc32a1 (assay MGI:7543886).
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S1B Oprm1 , S1B Merge High levels of colocalization are seen with Slc17a6, low levels with Slc32a1.
Specimen S6A - Htr2a: postnatal adult (more )
Note: Triple labeled: green - Oprm1; red - Htr2a (assay MGI:7543895); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S6A Htr2a High levels of colocalization are seen with Htr2a.
Specimen S6A - Cckar: postnatal adult (more )
Note: Triple labeled: green - Oprm1; red - Cckar (assay MGI:7543897); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S6A Cckar High levels of colocalization are seen with Cckar.
Specimen S6A - Tacr1: postnatal adult (more )
Note: Triple labeled: green - Oprm1; red - Tacr1 (assay MGI:7543898); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S6A Tacr1 High levels of colocalization are seen with Tacr1.
Specimen S6A - Tacr3: postnatal adult (more )
Note: Triple labeled: green - Oprm1; red - Tacr3 (assay MGI:7543899); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S6A Tacr3 High levels of colocalization are seen with Tacr3.
Specimen S6A - Drd5: postnatal adult (more )
Note: Triple labeled: green - Oprm1; red - Drd5 (assay MGI:7543900); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus central nervous system neuron Present S6A Drd5 High levels of colocalization are seen with Drd5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory