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Gene Expression Data
Assay Details
Assay
Reference: J:201042 Saito Y, et al., The septum transversum mesenchyme induces gall bladder development. Biol Open. 2013 Aug 15;2(8):779-88
Assay type: RNA in situ
MGI Accession ID: MGI:7543629
Gene symbol: Sox17
Gene name: SRY (sex determining region Y)-box 17
Probe: Sox17 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Present 1A Expressed in the pancreatobiliary common progenitor cells in the same region as Pdx1.

Specimen 1C: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: foregut epithelium Present Regionally restricted 1C Sox17+/Pdx1- endodermal cells started to emerge in the ventral foregut.

Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present 1E
TS15: pancreas primordium ventral bud Present Regionally restricted 1E Expressed in the anterior portion.

Specimen 1G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: gallbladder primordium Present 1G

Specimen 1J: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Present 1J Expressed in the pancreatobiliary common progenitor cells. Positive region was separated from the Wt1+ septum transversum region.

Specimen 1L: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: foregut epithelium Present 1L Expressed in the ventral foregut adjacent to the Wt1-expressing septum transversum.

Specimen 1N: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS15: foregut epithelium Present Regionally restricted 1N Expressed in the ventral foregut adjacent to the Wt1-expressing septum transversum.

Specimen 1P: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present 1P The Sox17-expressing gall bladder primordium was surrounded by the Wt1-expressing region.

Specimen 3E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present 3E Positive gall bladder primordium emerged from the hepatic diverticulum.

Specimen 3F: embryonic day 9.5; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS15: foregut-midgut junction Weak 3F No formation of the gall bladder primordium.

Specimen 3G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: gallbladder primordium Present 3G

Specimen 3H: embryonic day 10.5; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS17: foregut-midgut junction Weak 3H No formation of the gall bladder primordium.

Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Present 4A

Specimen 4B: embryonic day 8.5; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Present 4B Similar as in the wild-type.

Specimen 4C: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: foregut epithelium Present Regionally restricted 4C Expressed in the ventral foregut.

Specimen 4D: embryonic day 9.0; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS14: foregut epithelium Weak Regionally restricted 4D Expression was significantly reduced in the ventral foregut compared with the wild-type.

Specimen 4E: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: gallbladder primordium Present 4E

Specimen 4G: embryonic day 9.75; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS16: pancreas primordium ventral bud Present Regionally restricted 4G Only expressed in the anterior portion of the ventral pancreatic bud.

Specimen 6E: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: gallbladder primordium Present 6E

Specimen 6G: embryonic day 9.75; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS16: pancreas primordium ventral bud Present Regionally restricted 6G Only expressed in part of the anterior region.

Specimen 6O: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS15: foregut epithelium Present Regionally restricted 6O Expressed in the ventral foregut.

Specimen 6Q: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present 6Q
TS15: pancreas primordium ventral bud Present 6Q
TS15: hepatic primordium Absent 6Q

Specimen 6S: embryonic day 9.25; Mab21l2tm1Nao/Mab21l2tm1Nao (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present 6S
TS15: pancreas primordium ventral bud Present 6S
TS15: hepatic primordium Absent 6S Not expressed in the Alb+ hepatic region.

Specimen S4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present S4A

Specimen S4C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: gallbladder primordium Present S4C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory