Tg(CMV-APPSwe)3Wcx
Transgene Detail
|
|
| Symbol: |
Tg(CMV-APPSwe)3Wcx |
| Name: |
transgene insertion 3, Wen-Cheng Xiong |
| MGI ID: |
MGI:7543606 |
| Synonyms: |
LSL-APPswe, Tg(flox)APPswe |
| Transgene: |
Tg(CMV-APPSwe)3Wcx Location: unknown
|
| Alliance: |
Tg(CMV-APPSwe)3Wcx page
|
|
| Strain of Origin: |
Not Applicable
|
|
| Transgene Type: |
|
Transgenic (Conditional ready, Humanized sequence, Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The transgene consists of the CMV promoter, a loxP-flanked STOP sequence, human APP with the Swedish familial Alzheimer disease mutations (K670N, M671L) and polyA.
(J:329848)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:329848 Xia WF, et al., Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine. J Bone Miner Res. 2013 Oct;28(10):2122-35 |
| All: |
2 reference(s) |
|
Analysis Tools
