Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Htr2aem2(cre)Blr
Name:	5-hydroxytryptamine (serotonin) receptor 2A; endonuclease-mediated mutation 2, Bryan L Roth
MGI ID:	MGI:7543066
Synonyms:	Htr2aCre, Htr2a-IRES-Cre
Gene:	Htr2a  Location: Chr14:74878314-74944299 bp, + strand  Genetic Position: Chr14, 39.37 cM
Alliance:	Htr2aem2(cre)Blr page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Htr2aem2(cre)Blr expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Htr2a (MGI:109521)   Mutation details: IRES-Cre was introduced between the stop codon in exon 3 and the 3' UTR of the mouse Htr2a gene (chr14:74706397 in the GRCm38/mm10 genome assembly) using CRISPR/cas9 methodologies. (J:341620)

Activity:	Tissue activity of this recombinase allele
Driver:	Htr2a (mouse) Summary of all recombinase alleles driven by Htr2a. Alliance mouse Htr2a gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htr2a Mutation:	42 strains or lines available

Original:	J:341620 Chiu YT, et al., A suite of engineered mice for interrogating psychedelic drug actions. bioRxiv. 2023 Sep 26;
All:	1 reference(s)