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Gene Expression Data
Assay Details
Assay
Reference: J:317897 Gruzdev A, et al., PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth. Prostaglandins Other Lipid Mediat. 2012 Mar;97(3-4):109-19
Assay type: RNA in situ
MGI Accession ID: MGI:7541308
Gene symbol: Ptger4
Gene name: prostaglandin E receptor 4 (subtype EP4)
Probe: Ptger4 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: ductus arteriosus blood vessel smooth muscle cell Strong 1A Expressed in the layers containing the smooth muscle cells.
TS26: ductus arteriosus endothelial cell of artery Present 1A
Specimen 1C: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: ductus arteriosus blood vessel smooth muscle cell Strong 1C An abrupt change in expression was observed at the junction between the smooth muscle cells of the ductus arteriosus and the aorta.
TS27: aorta aortic smooth muscle cell Ambiguous 1C With little to no expression.
TS27: aorta aortic endothelial cell Present 1C
TS27: ductus arteriosus endothelial cell of artery Present 1C
Specimen 1E: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: aorta aortic endothelial cell Present 1E
TS27: aorta aortic smooth muscle cell Ambiguous 1E With little to no expression.
Specimen 1G: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: pulmonary trunk smooth muscle cell of the pulmonary artery Trace 1G Little expression was detected.
TS27: pulmonary trunk pulmonary artery endothelial cell Present 1G
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory