About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:145448 Shimoda H, Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development. Histochem Cell Biol. 2009 Feb;131(2):231-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539711
Gene symbol: Angpt2
Gene name: angiopoietin 2
Antibody: anti-Ang2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1a: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: anterior cardinal vein endothelial cell Present Regionally restricted 1a Expression is in a subpopulation of endothelial cells to one side of anterior cardinal veins and the budding lymphatic vessels.
TS19: lymphatic system endothelial cell Present Regionally restricted 1a Expression is in a subpopulation of endothelial cells to one side of anterior cardinal veins and the budding lymphatic vessels.

Specimen 2a: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: jugular lymph sac endothelial cell Present Regionally restricted 2a Expression is in the endothelial cells of jugular lymph sac.
TS22: lymphatic vessel endothelium endothelial cell Present Regionally restricted 2a Expression is in the endothelial cells of jugular lymph sac.

Specimen 2d: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: lymphatic system endothelial cell Present Regionally restricted 2d Expression is in the endothelial cells of thoracic duct.
TS22: lymphatic vessel endothelium endothelial cell Present Regionally restricted 2d Expression is in the endothelial cells of thoracic duct.

Specimen 2g: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelium endothelial cell Present Regionally restricted 2g Expression is in the endothelial cells of lymphatic vasculature around axillary vein.

Specimen 3a: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: lymphatic vessel endothelium endothelial cell Present Regionally restricted 3a Expression is in lymphatic endothelial cells around bronchus and pulmonary artery.

Specimen 3c: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: liver sinusoid endothelial cell Very strong 3c Expression is in hepatic sinusoidal capillaries and central vein.
TS24: liver vascular element endothelial cell Very strong 3c Expression is in hepatic sinusoidal capillaries and central vein.
TS24: hepatic portal vein Absent 3c

Specimen 3e: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: blood vessel endothelium blood vessel endothelial cell Present 3e
TS24: blood vessel endothelium endothelial cell Present 3e
TS24: lymphatic vessel endothelium blood vessel endothelial cell Present 3e
TS24: lymphatic vessel endothelium endothelial cell Present 3e

Specimen 3h: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: lymphatic vessel endothelium endothelial cell Present 3h

Specimen 3j: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lymphatic vessel Present Regionally restricted 3j Expression is in central lacteals and submucosal lymphatics continuous with the lacteals in small intestinal wall.
TS26: small intestine wall Present Regionally restricted 3j Expression is in central lacteals and submucosal lymphatics continuous with the lacteals in small intestinal wall.

Specimen 3k: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: adrenal medulla Very strong Regionally restricted 3k Expression is in the blood vasculature of adrenal medulla.
TS26: blood vessel Very strong Regionally restricted 3k Expression is in the blood vasculature of adrenal medulla.

Specimen 5a: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: lymph node endothelial cell Present Regionally restricted 5a Expression is in endothelial cells of marginal and medullary sinuses.

Specimen 5d: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: lymphatic vessel endothelium endothelial cell Present Regionally restricted 5d Expression is in endothelial cells of lymphatic vasculature in the lung.
TS27: blood vessel endothelium blood vessel endothelial cell Present Regionally restricted 5d Expression is in the endothelium of blood vessels as pulmonary arteries and alveolar capillaries.
TS27: lung vascular element blood vessel endothelial cell Present Regionally restricted 5d Expression is in the endothelium of blood vessels as pulmonary arteries and alveolar capillaries.
TS27: pulmonary artery blood vessel endothelial cell Present Regionally restricted 5d Expression is in the endothelium of blood vessels as pulmonary arteries and alveolar capillaries.

Specimen 6a: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: lymphatic vessel endothelium endothelial cell Present 6a
TS24: thoracic aorta endothelial cell Present 6a

Specimen 6b: postnatal day 7 (more )
Note: Double labeled: brown - Angpt2; blue - Prox1 (assay MGI:7539743).
Structure Level Pattern Image Note
TS28: lymphatic system Weak Regionally restricted 6b Expression is in the jugular lymph sac and is stronger in the small lymphatics.
TS28: carotid artery Absent 6b

Specimen 6d: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hyaloid vascular plexus Present 6d
TS24: blood vessel Present Regionally restricted 6d Expression is in retinal blood vessels.
TS24: retina Present Regionally restricted 6d Expression is in retinal blood vessels.

Specimen 6e: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: blood vessel Present Regionally restricted 6e Expression is in small blood vessels.
TS27: renal medulla Present Regionally restricted 6e Expression is in small blood vessels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory