Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tacr1tm1.1(cre/ERT2)Ddg
Name:	tachykinin receptor 1; targeted mutation 1.1, David D Ginty
MGI ID:	MGI:7539708
Synonyms:	Tacr1CreERT2
Gene:	Tacr1  Location: Chr6:82379315-82537085 bp, + strand  Genetic Position: Chr6, 35.94 cM, cytoband D1
Alliance:	Tacr1tm1.1(cre/ERT2)Ddg page

Germline Transmission:	Earliest citation of germline transmission: J:297417
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tacr1tm1.1(cre/ERT2)Ddg expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tacr1 (MGI:98475)   Mutation details: A Cre recombinase-estrogen receptor T2 (CreERT2) fusion cassettes were introduced via homologous recombination into the Tacr1 genes, replacing the first coding ATG. The neomycin selection cassette was removed by recombination. (J:297417)

Activity:	Tissue activity of this recombinase allele
Driver:	Tacr1 (mouse) Summary of all recombinase alleles driven by Tacr1. Comparative matrix view of recombinase activities Alliance mouse Tacr1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tacr1 Mutation:	40 strains or lines available

Original:	J:297417 Choi S, et al., Parallel ascending spinal pathways for affective touch and pain. Nature. 2020 Nov;587(7833):258-263
All:	1 reference(s)