About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:116501 Fukami M, et al., CXorf6 is a causative gene for hypospadias. Nat Genet. 2006 Dec;38(12):1369-71
Assay type: RNA in situ
MGI Accession ID: MGI:7539148
Gene symbol: Mamld1
Gene name: mastermind-like domain containing 1
Probe: G630014P10Rik cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2a E11.5 testis: embryonic day 11.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS19: gonad Weak Regionally restricted 2a E11.5 Testis Expressed in the internal region.

Specimen 2a E11.5 ovary: embryonic day 11.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted 2a E11.5 Ovary Expressed in a small number of somatic cells, primarily at the boundary to the mesonephros.

Specimen 2a E12.5 testis: embryonic day 12.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Cell Type Level Pattern Image Note
TS20: testis Present 2a E12.5 Testis
TS20: Sertoli cell Sertoli cell Present 2a E12.5 Testis inset
TS20: Leydig cell Leydig cell Present Single cells 2a E12.5 Testis Expressed in a small number of cells.

Specimen 2a E12.5 ovary: embryonic day 12.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS20: ovary Present Regionally restricted 2a E12.5 Ovary Expressed in a small number of somatic cells, primarily at the boundary to the mesonephros.

Specimen 2a E14.5 testis: embryonic day 14.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present 2a E14.5 Testis
TS22: Leydig cell Leydig cell Present 2a E14.5 Testis , 2a E14.5 Testis inset Expressed in the majority of cells.

Specimen 2a E14.5 ovary: embryonic day 14.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS22: ovary Weak Regionally restricted 2a E14.5 Ovary Expressed in a small number of somatic cells in the internal region.
TS22: paramesonephric duct of female Present 2a E14.5 Ovary

Specimen 2b birth testis: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: seminiferous cord Trace 2b birth Testis

Specimen 2b birth ovary: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: ovary Absent 2b birth Ovary

Specimen 2b 1w testis: postnatal week 1 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Weak 2b 1w Testis

Specimen 2b 1w ovary: postnatal week 1 (more )
Structure Level Pattern Image Note
TS28: ovary Absent 2b 1w Ovary

Specimen 2b 2w testis: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Trace 2b 2w Testis

Specimen 2b 2w ovary: postnatal week 2 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary follicle cell granulosa cell Trace 2b 2w Ovary

Specimen 2b 3w testis: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Trace 2b 3w Testis

Specimen 2b 3w ovary: postnatal week 3 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary follicle cell granulosa cell Present Regionally restricted 2b 3w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.
TS28: ovary mature follicle granulosa cell Present Regionally restricted 2b 3w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.

Specimen 2b 8w testis: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Trace 2b 8w Testis

Specimen 2b 8w ovary: postnatal week 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary follicle cell granulosa cell Present Regionally restricted 2b 8w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.
TS28: ovary mature follicle granulosa cell Present Regionally restricted 2b 8w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: external genitalia Weak Expressed at a level similar to that detected in the neighboring extragenital tissues.
TS20: male external genitalia Weak Diffuse
TS20: adrenal primordium Absent
TS20: forebrain Present
TS20: pancreas Present
TS20: paramesonephric duct Present
TS20: somite Present
TS20: spinal cord Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory