Dcx Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:332746 Navas-Perez E, et al., Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Genome Biol. 2020 Oct 26;21(1):267
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7537427
Gene symbol:	Dcx
Gene name:	doublecortin

Antibody:	anti-doublecortin
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

5F DCX WT ©

Specimen 5F WT: postnatal adult (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: dentate gyrus	dentate gyrus neuron	Present		5F DCX WT	Expression in immature neurons.

5F DCX KO ©

Specimen 5F KO: postnatal adult; Bex3^em1Jjcar/Bex3^em1Jjcar (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: dentate gyrus	dentate gyrus neuron	Weak		5F DCX KO	Significant and selective reduction in number of immature neurons compared to wild type.

Specimen 5F delta(14-72): postnatal adult; Bex3^em2Jjcar/Bex3^em2Jjcar (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: dentate gyrus	dentate gyrus neuron	Present		5F DCX delta(24-72)	No significant difference compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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