Acan Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:221086 Patra D, et al., Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7537308
Gene symbol:	Acan
Gene name:	aggrecan

Antibody:	anti-aggrecan
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

3I ©

Specimen 3I: embryonic day 16.5; Mbtps1^tm1Jdh/Mbtps1^tm1Jdh (more

)
Note: Double labeled: red - Acan; green - Canx (assay MGI:7537301).

Structure	Level	Pattern	Image	Note
TS24: femur	Present		3I

3J ©

Specimen 3J: embryonic day 16.5; Mbtps1^tm1Jdh/Mbtps1^tm1Jdh, Tg(Col2a1-cre)1Bhr/0 (more

)
Note: Conditional mutant. Double labeled: red - Acan; green - Canx (assay MGI:7537301).

Structure	Level	Pattern	Image	Note
TS24: femur	Present		3J	Authors state that S1P ablation does not affect secretion.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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