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Gene Expression Data
Assay Details
Assay
Reference: J:185975 Baker C, et al., Adrenergic deficiency leads to impaired electrical conduction and increased arrhythmic potential in the embryonic mouse heart. Biochem Biophys Res Commun. 2012 Jul 6;423(3):536-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7537184
Gene symbol: Hcn4
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Antibody: anti-HCN4 (AB5808)
Detection system: Secondary antibody
Results
Specimen 1a/c: embryonic day 10.5 (more )
Note: The genotype could be either +/+ or +/-. Double labeled: green - Hcn4; red - Gja1 (assay MGI:7537183).
Structure Level Pattern Image Note
TS17: sinoatrial node Present 1a , 1c

Specimen 1b/d: embryonic day 10.5; Dbhtm1Rpa/Dbhtm1Rpa (more )
Note: Double labeled: green - Hcn4; red - Gja1 (assay MGI:7537183).
Structure Level Pattern Image Note
TS17: sinoatrial node Present 1d , 1b Similar as in the controls.

Specimen 1e: embryonic day 10.5 (more )
Note: The genotype could be either +/+ or +/-. Double labeled: green - Hcn4; red - Actn2 (assay MGI:7537185).
Structure Level Pattern Image Note
TS17: sinoatrial node Present 1e

Specimen 1f: embryonic day 10.5; Dbhtm1Rpa/Dbhtm1Rpa (more )
Note: Double labeled: green - Hcn4; red - Actn2 (assay MGI:7537185).
Structure Level Pattern Image Note
TS17: sinoatrial node Present 1f Similar as in the controls.

Specimen 2a: embryonic day 9.5 (more )
Note: The genotype could be either +/+ or +/-.
Structure Level Pattern Image Note
TS15: heart Present 2a

Specimen 2b: embryonic day 9.5; Dbhtm1Rpa/Dbhtm1Rpa (more )
Structure Level Pattern Image Note
TS15: heart Present 2b Similar as in the controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory