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Gene Expression Data
Assay Details
Assay
Reference: J:238708 Gonen N, et al., Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone. PLoS Genet. 2017 Jan;13(1):e1006520
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7536983
Gene symbol: Foxl2
Gene name: forkhead box L2
Antibody: Anti-Foxl2 (C terminus)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Assay notes: The antibody reference described 2 antibodies: MGI:5618299 and MGI:5640581. The one used in this assay was not specified.
Results
Specimen 2B E12.5 wild type: embryonic day 12.5 (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS20: primary sex cord Absent 2B E12.5 XY wild type Merged (+Dapi) , 2B E12.5 XY wild type Foxl2
Specimen 2B E12.5 TESCO-/-: embryonic day 12.5; Rr505em1Rlb/Rr505em1Rlb (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS20: primary sex cord Absent 2B E12.5 XY Tesco-/- Foxl2 , 2B E12.5 XY Tesco-/- Merged (+Dapi) As in wild type, staining was not detected in the mutant.
Specimen 2B E14.5 wild type: embryonic day 14.5 (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS22: primary sex cord Absent 2B E14.5 XY wild type Foxl2 , 2B E14.5 XY wild type Merged (+Dapi)
Specimen 2B E14.5 TESCO-/-: embryonic day 14.5; Rr505em1Rlb/Rr505em1Rlb (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS22: primary sex cord Absent 2B E14.5 XY Tesco-/- Merged (+Dapi) , 2B E14.5 XY Tesco-/- Foxl2 As in wild type, staining was not detected in the mutant.
Specimen S2B E12.5 wild type: embryonic day 12.5 (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS20: ovary Present S2B E12.5 XX wild type Foxl2 , S2B E12.5 XX wild type Merged (+Dapi)
Specimen S2B E12.5 TESCO-/-: embryonic day 12.5; Rr505em1Rlb/Rr505em1Rlb (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS20: ovary Present S2B E12.5 XX Tesco-/- Merged (+Dapi) , S2B E12.5 XX Tesco-/- Foxl2 Staining in the TESCO-/- mutant was indistinguishable from wild type ovary.
Specimen S2B E14.5 wild type: embryonic day 14.5 (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS22: ovary Present S2B E14.5 XX wild type Merged (+Dapi) , S2B E14.5 XX wild type Foxl2
Specimen S2B E14.5 TESCO-/-: embryonic day 14.5; Rr505em1Rlb/Rr505em1Rlb (more )
Note: Double labeled: magenta - Foxl2; green - Amh (assay MGI:7536975).
Structure Level Pattern Image Note
TS22: ovary Present S2B E14.5 XX Tesco-/- Foxl2 , S2B E14.5 XX Tesco-/- Merged (+Dapi) Staining in the TESCO-/- mutant was indistinguishable from wild type ovary.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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