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Gene Expression Data
Assay Details
Assay
Reference: J:309492 Yaba A, et al., Expression of CCM2 and CCM3 during mouse gonadogenesis. J Assist Reprod Genet. 2015 Oct;32(10):1497-507
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7532724
Gene symbol: Pdcd10
Gene name: programmed cell death 10
Antibody: anti-CCM3/PDCD10
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 2a: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: germ cell of testis Present 2a Cytoplasmic expression in gonocytes in the lumen of the seminiferous cord.
TS21: Sertoli cell Sertoli cell Present 2a Cytoplasmic expression.
TS21: interstitium of the testis interstitial cell Present Regionally restricted 2a Cytoplasmic expression in interstitial cells around the cords.

Specimen 2b: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: germ cell of testis Present 2b Increased perinuclear cytoplasmic expression.
TS22: Sertoli cell Sertoli cell Present 2b Cytoplasmic expression.
TS22: interstitium of the testis interstitial cell Present 2b Cytoplasmic expression.

Specimen 2c: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: germ cell of testis Present 2c Some gonocytes showed cytoplasmic expression while others exhibited nuclear localization.
TS23: interstitium of the testis interstitial cell Present 2c Cytoplasmic expression.

Specimen 2d: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: germ cell of testis Present 2d Cytoplasmic expression in some gonocytes in mitotic silence.
TS25: Sertoli cell Sertoli cell Present 2d Cytoplasmic expression.
TS25: interstitium of the testis interstitial cell Present 2d Cytoplasmic expression.

Specimen 2e: postnatal day 0.5 (more )
Structure Cell Type Level Pattern Image Note
TS27: germ cell of testis Trace 2e Very weak expression in some gonocytes at the end of the mitotic silence.
TS27: interstitium of the testis interstitial cell Present 2e Decreased expression in some of the interstitial cells.
TS27: Sertoli cell Sertoli cell Absent 2e
TS27: developing vasculature of testis blood vessel endothelial cell Present 2e Nuclear expression.

Specimen 2f: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: Sertoli cell Sertoli cell Absent 2f
TS27: interstitium of the testis interstitial cell Present 2f Cytoplasmic expression.
TS27: developing vasculature of testis blood vessel endothelial cell Present 2f Nuclear expression.

Specimen 2g: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 2g
TS28: spermatogonium Present 2g Cytoplasmic expression.
TS28: vasculature of testis blood vessel endothelial cell Present 2g

Specimen 2h: postnatal day 9 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 2h
TS28: testis Absent 2h

Specimen 2i: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 2i
TS28: primary spermatocyte Present 2i Cytoplasmic expression in pachytene spermatocytes.

Specimen 2j: postnatal day 20 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 2j
TS28: primary spermatocyte Present 2j Increased expression in pachytene spermatocytes.
TS28: interstitium of the testis interstitial cell Present 2j

Specimen 2k: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent 2k
TS28: primary spermatocyte Trace 2k Very weak cytoplasmic expression in pachytene spermatocytes in VII-VIII stage.
TS28: spermatid Trace 2k Very weak cytoplasmic expression in distinctive, round spermatid and elongated spermatids in XI-XII stage.
TS28: interstitium of the testis interstitial cell Present 2k Similar as in PND 20.

Specimen 3b: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: oocyte Present 3b Cytoplasmic expression.
TS27: follicle cell of primordial follicle Present 3b

Specimen 3d: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: follicle cell of primordial follicle Present 3d
TS27: follicle cell of primary follicle granulosa cell Present 3d
TS27: oocyte Present 3d Cytoplasmic expression.

Specimen 3f: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: oocyte Present 3f Cytoplasmic expression. Dramatically increased through PND 1 to 9.
TS28: follicle cell of preantral follicle granulosa cell Present 3f
TS28: follicle cell of secondary follicle granulosa cell Present 3f
TS28: ovary growing follicle granulosa cell Present 3f

Specimen 3h: postnatal day 9 (more )
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of preantral follicle granulosa cell Present 3h
TS28: follicle cell of primary follicle granulosa cell Present 3h
TS28: follicle cell of primordial follicle granulosa cell Present 3h
TS28: follicle cell of secondary follicle granulosa cell Present 3h
TS28: oocyte Present 3h Increased nuclear expression.

Specimen 3j: postnatal week 12 (more )
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of antral follicle granulosa cell Present 3j
TS28: ovary growing follicle granulosa cell Present 3j
TS28: oocyte Present 3j Cytoplasmic expression.
TS28: corpus luteum luteal cell Strong 3j


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory