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Gene Expression Data
Assay Details
Assay
Reference: J:339054 Musa G, et al., Gpr126 (Adgrg6) is expressed in cell types known to be exposed to mechanical stimuli. Ann N Y Acad Sci. 2019 Nov;1456(1):96-108
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7532621
Gene symbol: Adgrg6
Gene name: adhesion G protein-coupled receptor G6
Reporter: lacZ
Direct Detection
Results
Specimen 2A - E9.5: embryonic day 9.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS15: heart Present Widespread 2A E9.5 inset , 2A E9.5
Specimen 2A - E11.5: embryonic day 11.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS19: heart Present Widespread 2A E11.5 inset , 2A E11.5
TS19: somite Present 2A E11.5
Specimen 2B - E9.5: embryonic day 9.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS15: endocardial lining cardiac endothelial cell Present 2B E9.5
TS15: cardiac muscle tissue cardiac muscle cell Absent 2B E9.5
Specimen 2B - E11.5: embryonic day 11.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS19: endocardial lining cardiac endothelial cell Present 2B E11.5
TS19: cardiac muscle tissue cardiac muscle cell Absent 2B E11.5
Specimen 2B - E12.5: embryonic day 12.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS20: endocardial lining cardiac endothelial cell Present 2B E12.5
TS20: cardiac muscle tissue cardiac muscle cell Absent 2B E12.5
Specimen 2B - E13.5: embryonic day 13.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS21: endocardial lining cardiac endothelial cell Present 2B E13.5
TS21: cardiac muscle tissue cardiac muscle cell Absent 2B E13.5
Specimen 2C - P5: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: endocardial lining Present 2C P5 , 2C P5 inset
Specimen 2C - Adult: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: heart Weak Regionally restricted 2C Adult inset , 2C Adult Staining is seen at the base of the heart.
TS28: endocardial lining Absent 2C Adult
Specimen 2D - P5 Atrium: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: atrium endocardial lining cardiac endothelial cell Present 2D P5 Atrium
Specimen 2D - P5 Ventricle: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: ventricle endocardial lining cardiac endothelial cell Present 2D P5 Ventricle
Specimen 2D - Adult Atrium: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: atrium endocardial lining cardiac endothelial cell Absent 2D Adult Atrium
Specimen 2D - Adult Ventricle: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: ventricle endocardial lining cardiac endothelial cell Absent 2D Adult Ventricle
Specimen 2E - P5: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: sciatic nerve Present 2E P5 inset , 2E P5
Specimen 2E - Adult: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: sciatic nerve Present 2E Adult inset , 2E Adult Staining levels are lower than at P5.
Specimen 3A - whole mount: embryonic day 12.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS20: umbilical cord Present 3A left
Specimen 3A - section: embryonic day 12.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS20: umbilical vein embryonic part endothelial cell of umbilical vein Present 3A right
TS20: umbilical artery embryonic part Absent 3A right
TS20: umbilical cord smooth muscle cell Absent 3A right
Specimen 3B - P5 Lung: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element lung endothelial cell Present 3B P5 Lung , 3B P5 Lung inset
Specimen 3B - Adult Lung: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element lung endothelial cell Present 3B Adult Lung inset , 3B Adult Lung
Specimen 3B - P5 Tongue: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: tongue blood vessel endothelial cell Present 3B P5 Tongue inset , 3B P5 Tongue
Specimen 3B - Adult Tongue: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: tongue blood vessel endothelial cell Present 3B Adult Tongue , 3B Adult Tongue inset
Specimen 3C - P5 Lung: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element lung endothelial cell Present 3C P5 Lung
TS28: lung Present 3C P5 Lung Staining is seen in non-vascular (and vascular) tissue.
Specimen 3C - Adult Lung: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element lung endothelial cell Present 3C Adult Lung
Specimen 3C - P5 Tongue: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: tongue blood vessel endothelial cell Present 3C P5 Tongue
Specimen 3C - Adult Tongue: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: tongue blood vessel endothelial cell Present 3C Adult Tongue
Specimen 3C - P5 Kidney: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present 3C P5 Kidney
Specimen 3C - Adult Kidney: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present 3C Adult Kidney
Specimen S1 - P5 Liver: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: hepatic portal vein Present S1_P5 Liver , S1_P5 Liver inset
Specimen S1 - P5 Stomach: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: stomach vascular element blood vessel endothelial cell Present S1_P5 Stomach inset , S1_P5 Stomach Staining is seen in the microvasculature.
Specimen S1 - Adult Skeletal muscle: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: skeletal muscle tissue blood vessel endothelial cell Present S1_Adult Skeletal muscle , S1_Adult Skeletal muscle inset
Specimen 3D - Large vessel: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Triple labeled: blue - Adgrg6 reporter; red - Pecam1 (assay MGI:7532623); blue - DAPI. Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: renal large blood vessel blood vessel endothelial cell Present 3D Large vessel right , 3D Large vessel left
Specimen 3D - Glomerulus: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Triple labeled: blue - Adgrg6 reporter; red - Pecam1 (assay MGI:7532623); blue - DAPI. Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: glomerular capillary system Absent 3D Glomerulus left , 3D Glomerulus right
Specimen 4A - E12.5: embryonic day 12.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS20: rib pre-cartilage condensation Present 4A E12.5 , 4A E12.5 inset
TS20: limb mesenchyme Present Regionally restricted 4A E12.5 inset , 4A E12.5 Staining is seen in embryonic limb joints.
Specimen 4A - E13.5: embryonic day 13.5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS21: rib cartilage condensation Present 4A E13.5 inset , 4A E13.5
TS21: limb joint Present 4A E13.5 inset , 4A E13.5
Specimen 4B - P5 Trachea: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: trachea cartilage Present 4B P5 Trachea , 4B P5 Trachea inset
Specimen 4B - Adult Trachea: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: trachea cartilage Present 4B Adult Trachea , 4B Adult Trachea inset
Specimen 4B - P5 Sternum: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: sternum Present 4B P5 Sternum inset , 4B P5 Sternum
Specimen 4B - Adult Sternum: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: sternum Present 4B Adult Sternum , 4B Adult Sternum inset
Specimen 4B - IVD: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: intervertebral disc Present 4B Adult IVD , 4B Adult IVD inset
Specimen 4C: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: trachea cartilage chondrocyte Present Regionally restricted 4C Staining is seen in some, but not all, chondrocytes.
Specimen 5A - P5 Kidney: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: metanephros Present 5A P5 Kidney inset , 5A P5 Kidney
Specimen 5A - P5 Bladder: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: bladder Present 5A P5 Bladder inset , 5A P5 Bladder
Specimen 5A - Adult Ureter: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: ureter Present 5A Adult Ureter , 5A Adult Ureter inset
Specimen 5A - P5 Salivary gland: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 5A P5 Salivary gland , 5A P5 Salivary gland inset Staining is seen in the secretory parenchyma.
Specimen 5B - P5: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: urothelium of bladder umbrella cell of urothelium Present 5B P5 Staining is seen in the transitional epithelium.
Specimen 5B - Adult: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: urothelium of bladder umbrella cell of urothelium Present 5B Adult Staining is seen in the transitional epithelium.
Specimen 5C - P5 Ureter: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: urothelium of ureter Present 5C P5 Ureter Staining is seen in the transitional epithelium.
Specimen 5C - Adult Ureter: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: urothelium of ureter Present 5C Adult Ureter Staining is seen in the transitional epithelium.
Specimen 5C - P5 Kidney: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: collecting duct epithelium Present 5C P5 Kidney
Specimen 5C - Adult Kidney: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: collecting duct epithelium Present 5C Adult Kidney
Specimen 5D: postnatal day 5; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Cell Type Level Pattern Image Note
TS28: salivary gland acinar cell of salivary gland Present 5D
Specimen S2A: postnatal adult; Adgrg6tm1a(EUCOMM)Hmgu/Adgrg6+ (more )
Note: Tissue fixative included 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: spleen Absent S2A The authors were concerned about the lack of staining in this tissue as other types of studies suggested expression should be present in it.
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03/25/2025
MGI 6.24 		The Jackson Laboratory