Gene Expression Data
Assay Details
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Assay
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Reference:
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J:336094
Zheng H, et al., CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7532564
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Gene symbol:
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Dspp
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Gene name:
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dentin sialophosphoprotein
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Results
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Specimen
4A:
embryonic day 16.5
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4B:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Stub1tm1Cpat/Stub1tm1Cpat
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4C:
embryonic day 18.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: molar |
odontoblast |
Present |
Regionally restricted |
4C
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Odontoblasts at the cusp region started to express Dspp.
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| TS26: molar mesenchyme |
mesenchymal cell |
Present |
Regionally restricted |
4C
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Expression was detected in the dental mesenchymal cells at the cusp region.
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Specimen
4D:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Stub1tm1Cpat/Stub1tm1Cpat
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: molar |
odontoblast |
Present |
Regionally restricted |
4D
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Expression in the mutant was stronger than in control.
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| TS26: molar mesenchyme |
mesenchymal cell |
Present |
Regionally restricted |
4D
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Expression in the mutant was stronger than in control.
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Specimen
4E:
postnatal day 1
(more )
Specimen
4E:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4F:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Stub1tm1Cpat/Stub1tm1Cpat
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: molar |
odontoblast |
Present |
Regionally restricted |
4F
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Differentiating odontoblasts had higher expression in the mutant compared with wild type.
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| TS27: molar |
ameloblast |
Present |
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4F
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Expression was increased in the mutant ameloblasts compared with wild type.
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Specimen
S1A:
postnatal day 2
(more )
Specimen
S1A:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools