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Gene Expression Data
Assay Details
Assay
Reference: J:238642 Vrbacky M, et al., Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice. Hum Mol Genet. 2016 Nov 01;25(21):4674-4685
Assay type: Western blot
MGI Accession ID: MGI:7531708
Gene symbol: Atp5mc3
Gene name: ATP synthase membrane subunit c locus 3
Antibody: anti-c-Fo
Detection system: Secondary antibody
Assay notes: The specificity of the antibody used was not detailed; all family members have been annotated.
Results Image: 2A F0-c
 Sample Information Bands Other Sample Information
Lane AgeStructure 600 kDa (a) Genetic BackgroundMutant Allele(s)Sex
+/+ E9.5 TS15: embryo Present involves: C57BL/6N Not Specified
-/- E9.5 TS15: embryo Weak (b) involves: C57BL/6N Tmem70tm1a(KOMP)Wtsi/Tmem70tm1a(KOMP)WtsiNot Specified
+/- E9.5 TS15: embryo Present (c) involves: C57BL/6N Tmem70tm1a(KOMP)Wtsi/Tmem70+Not Specified
Notes:
(a) fully assembled ATP synthase complex (F1Fo, CV)
(b) An around 80% decrease in expression compared with wild-type.
(c) Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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