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Gene Expression Data
Assay Details
Assay
Reference: J:281166 Zhang X, et al., Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis. Nat Commun. 2019 Sep 13;10(1):4158
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531405
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen S2b Ifnar1-/-Ripk1+/+: embryonic day 12.5; Ifnar1tm1Agt/Ifnar1tm1Agt (more )
Structure Level Pattern Image Note
TS20: liver Ambiguous S2b lower left Trace or absent.

Specimen S2b Ifnar1-/-Ripk1 K376R/K376R: embryonic day 12.5; Ripk1em3Hbz/Ripk1em3Hbz, Ifnar1tm1Agt/Ifnar1tm1Agt (more )
Structure Level Pattern Image Note
TS20: liver Present S2b lower right

Specimen S2c Tnfr1-/-Ripk1+/+ skin: postnatal week 1; Tnfrsf1atm1Imx/Tnfrsf1atm1Imx (more )
Structure Level Pattern Image Note
TS28: skin Ambiguous S2c upper left Trace or absent.

Specimen S2c Tnfr1-/-Ripk1 K376R/K376R skin: postnatal week 1; Ripk1em3Hbz/Ripk1em3Hbz, Tnfrsf1atm1Imx/Tnfrsf1atm1Imx (more )
Structure Level Pattern Image Note
TS28: skin Ambiguous S2c upper right Trace or absent. No significantly positive cells detected.

Specimen S2c Tnfr1-/-Ripk1+/+ intestine: postnatal week 1; Tnfrsf1atm1Imx/Tnfrsf1atm1Imx (more )
Structure Level Pattern Image Note
TS28: intestine Ambiguous S2c middle left Trace or absent.

Specimen S2c Tnfr1-/-Ripk1 K376R/K376R intestine: postnatal week 1; Ripk1em3Hbz/Ripk1em3Hbz, Tnfrsf1atm1Imx/Tnfrsf1atm1Imx (more )
Structure Level Pattern Image Note
TS28: intestine Ambiguous S2c middle right Trace or absent. No significantly positive cells detected.

Specimen S2c Tnfr1-/-Ripk1+/+ liver: postnatal week 1; Tnfrsf1atm1Imx/Tnfrsf1atm1Imx (more )
Structure Level Pattern Image Note
TS28: liver Ambiguous S2c lower left Trace or absent.

Specimen S2c Tnfr1-/-Ripk1 K376R/K376R liver: postnatal week 1; Ripk1em3Hbz/Ripk1em3Hbz, Tnfrsf1atm1Imx/Tnfrsf1atm1Imx (more )
Structure Level Pattern Image Note
TS28: liver Ambiguous S2c lower right Trace or absent. No significantly positive cells detected.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory