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Gene Expression Data
Assay Details
Assay
Reference: J:330533 Bakalar D, et al., Lack of placental neurosteroid alters cortical development and female somatosensory function. Front Endocrinol (Lausanne). 2022;13:972033
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529476
Gene symbol: Cux1
Gene name: cut-like homeobox 1
Antibody: CDP Antibody (C-20): sc-6327
Detection system: Secondary antibody
Results
Specimen 3A Ctrl: postnatal day 30; Akr1c14tm1.1Penn/Akr1c14tm1.1Penn (more )
Structure Cell Type Level Pattern Image Note
TS28: cortical layer II pyramidal neuron Present 3A Cux1 Ctrl
TS28: cortical layer III pyramidal neuron Present 3A Cux1 Ctrl
TS28: cortical layer IV pyramidal neuron Present 3A Cux1 Ctrl
Specimen 3A pIKO: postnatal day 30; Akr1c14tm1.1Penn/Akr1c14tm1.1Penn, Tg(Cyp19a1-cre)5912Gle/0 (more )
Note: Conditional mutant. Double labeled: red - Cux1; cyan - Foxp2 (assay MGI:7529478).
Structure Cell Type Level Pattern Image Note
TS28: cortical layer II pyramidal neuron Present 3A Cux1 pIKO , 3A merge Significant reduction of positive neurons compared with controls (quantified in Fig 3B).
TS28: cortical layer III pyramidal neuron Present 3A Cux1 pIKO , 3A merge Significant reduction of positive neurons compared with controls (quantified in Fig 3B).
TS28: cortical layer IV pyramidal neuron Present 3A Cux1 pIKO , 3A merge Significant reduction of positive neurons compared with controls (quantified in Fig 3B).
Specimen not shown: postnatal day 30; Akr1c14tm1.1Penn/Akr1c14tm1.1Penn (more )
Structure Cell Type Level Pattern Image Note
TS28: cortical layer II pyramidal neuron Present
TS28: cortical layer III pyramidal neuron Present
TS28: cortical layer IV pyramidal neuron Present
Specimen not shown: postnatal day 30; Akr1c14tm1.1Penn/Akr1c14tm1.1Penn, Tg(Cyp19a1-cre)5912Gle/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: cortical layer II pyramidal neuron Present Similar as in the control males (quantified in Fig 3B).
TS28: cortical layer III pyramidal neuron Present Similar as in the control males (quantified in Fig 3B).
TS28: cortical layer IV pyramidal neuron Present Similar as in the control males (quantified in Fig 3B).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory