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Gene Expression Data
Assay Details
Assay
Reference: J:256718 Shimbo M, et al., Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2. PLoS One. 2017;12(12):e0190333
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7528930
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Antibody: anti-collagen type X
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4E control: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: tibia hypertrophic chondrocyte Present Regionally restricted 4E E18.5 control Expression is in hypertrophic chondrocytes in the tibial growth plates.
Specimen 4E Col2-DKO: embryonic day 18.5; Csgalnact1tm1Nari/Csgalnact1tm1Nari, Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: tibia hypertrophic chondrocyte Present 4E E18.5 Col2-DKO Expression in this mutant is the same as in controls.
Specimen 4E P14 control: postnatal day 14 (more )
Structure Cell Type Level Pattern Image Note
TS28: tibia hypertrophic chondrocyte Present Regionally restricted 4E P14 control There is uniform epression in the hypertrophic chondrocytes in the hypertrophic zone.
Specimen 4E P14 Col2-DKO: postnatal day 14; Csgalnact1tm1Nari/Csgalnact1tm1Nari, Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: tibia hypertrophic chondrocyte Present Regionally restricted 4E P14 Col2-DKO Expression was distributed irregularly in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory