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Gene Expression Data
Assay Details
Assay
Reference: J:118579 Brandt-Bohne U, et al., MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system. Biochem J. 2007 Jan 15;401(2):447-57
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526783
Gene symbol: Megf9
Gene name: multiple EGF-like-domains 9
Antibody: anti-Megf9 (pAbKR18)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Strong Graded 5A Expression is stronger in the outer layers.
TS26: cerebellum Present 5A
TS26: cranial ganglion Present 5A
TS26: cranial nerve Present 5A
TS26: diencephalon Present 5A
TS26: facial nucleus Present 5A
TS26: inferior colliculus Present 5A
TS26: nerve Present 5A
TS26: superior colliculus Present 5A
TS26: trigeminal ganglion Present 5A
TS26: trigeminal nerve Present 5A
TS26: medulla oblongata Present Regionally restricted 5A Expression is dorsal.
TS26: brain Present Widespread 5A Expression is in all structures.
Specimen 5B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: neocortex layer Strong Graded 5B Expression is stronger in the outer layers.
TS27: cerebellum Present 5B
TS27: cranial ganglion Present 5B
TS27: cranial nerve Present 5B
TS27: diencephalon Present 5B
TS27: facial nucleus Present 5B
TS27: inferior colliculus Present 5B
TS27: nerve Present 5B
TS27: superior colliculus Present 5B
TS27: trigeminal ganglion Present 5B
TS27: trigeminal nerve Present 5B
TS27: medulla oblongata Present Regionally restricted 5B Expression is dorsal.
TS27: brain Present Widespread 5B Expression is in all structures.
Specimen 5C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum Strong 5C
Specimen 5D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 5D
Specimen 5E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus stratum oriens Strong 5E
TS28: hippocampus stratum radiatum Strong 5E
TS28: hippocampus CA1 Strong Regionally restricted 5E Absent in the nuclear layer.
TS28: hippocampus CA2 Present Regionally restricted 5E Absent in the nuclear layer.
Specimen 5F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5F
Specimen 5G: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Present 5G
Specimen 5H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present Regionally restricted 5H Expression is in the anterior lens.
Specimen 5I: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: lens Present 5I
TS27: retina ganglion cell layer Present 5I
Specimen 5J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: Bruch's membrane Present 5J
TS28: photoreceptor layer outer segment Present 5J
TS28: retina inner plexiform layer Present 5J
TS28: retina outer plexiform layer Present 5J
TS28: retina layer Present Regionally restricted 5J Expression is in the interneural layers and is absent in the nuclear layers.
TS28: pigmented retinal epithelium Absent 5J
TS28: retina nuclear layer Absent 5J
Specimen 5K: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord dorsal horn Present 5K
TS26: spinal nerve ventral root Present 5K
TS26: thoracic ganglion Present 5K
Specimen 5L: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Present 5L
Specimen 5M: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: thoracic ganglion Present 5M
Specimen 5N: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present 5N
Specimen 6A: postnatal (more )
Note: Double labeled: red - Megf9; green -a glia-specific lectin (IB4).
Structure Cell Type Level Pattern Image Note
TS28: sciatic nerve glial cell Present Single cells 6A Expression is in satellite glia cells.
Specimen 6B: postnatal (more )
Note: Double labeled: red - Megf9; green -a glia-specific lectin (IB4).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion glial cell Present Single cells 6B Expression is around dorsal root nerves in glial cells.
Specimen 6C: postnatal (more )
Note: Double labeled: red - Megf9; green - Lamc1 (assay MGI:7526791).
Structure Cell Type Level Pattern Image Note
TS28: basement membrane Schwann cell Present Regionally restricted 6C Expression is in the basement membranes of Schwann cells.
TS28: sciatic nerve Schwann cell Present Regionally restricted 6C Expression is in the basement membranes of Schwann cells.
Specimen 6D: postnatal (more )
Note: Double labeled: red - Megf9; green - Nefh (assay MGI:7526792).
Structure Cell Type Level Pattern Image Note
TS28: sciatic nerve glial cell Present Regionally restricted 6D Expression is on glia throughout peripheral nerves.
Specimen 6E: postnatal (more )
Note: Double labeled: red - Megf9; green - Nefh (assay MGI:7526792).
Structure Cell Type Level Pattern Image Note
TS28: sciatic nerve glial cell Present Regionally restricted 6E Expression is on glia throughout peripheral nerves.
Specimen 6F: postnatal (more )
Note: Double labeled: red - Megf9; green - Gfap (assay MGI:7526793).
Structure Cell Type Level Pattern Image Note
TS28: sciatic nerve glial cell Present Regionally restricted 6F Expression is on glia throughout peripheral nerves.
Specimen 6J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: trigeminal nerve Present 6J
Specimen 7A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: brain Strong 7A
TS27: trigeminal nerve Strong 7A
TS27: epidermis basal layer Present 7A
TS27: epidermis cornified layer Present 7A
TS27: epidermis granular layer Present 7A
TS27: epidermis spinous layer Present 7A
TS27: epidermis stratum lucidum Present 7A
TS27: epidermis suprabasal layer Present 7A
TS27: hair outer root sheath Present 7A
Specimen 7B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis basal layer Present Regionally restricted 7B Expression is in skin and around hair follicles.
TS27: epidermis cornified layer Present Regionally restricted 7B Expression is in skin and around hair follicles.
TS27: epidermis granular layer Present Regionally restricted 7B Expression is in skin and around hair follicles.
TS27: epidermis spinous layer Present Regionally restricted 7B Expression is in skin and around hair follicles.
TS27: epidermis stratum lucidum Present Regionally restricted 7B Expression is in skin and around hair follicles.
TS27: epidermis suprabasal layer Present Regionally restricted 7B Expression is in skin and around hair follicles.
TS27: hair outer root sheath Present Regionally restricted 7B Expression is in skin and around hair follicles.
Specimen 7C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis basal layer Present 7C
TS27: epidermis cornified layer Present 7C
TS27: epidermis granular layer Present 7C
TS27: epidermis spinous layer Present 7C
TS27: epidermis stratum lucidum Present 7C
TS27: epidermis suprabasal layer Present 7C
TS27: hair outer root sheath Present 7C
Specimen 7D: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: filiform papillae keratinocyte Present 7D
Specimen 7E: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: filiform papillae keratinocyte Present 7E
Specimen 7F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: esophagus epithelium Present 7F
Specimen 7G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine epithelium Present 7G
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory