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Gene Expression Data
Assay Details
Assay
Reference: J:253527 Geng R, et al., Comprehensive Expression of Wnt Signaling Pathway Genes during Development and Maturation of the Mouse Cochlea. PLoS One. 2016;11(2):e0148339
Assay type: RNA in situ
MGI Accession ID: MGI:7526742
Gene symbol: Frzb
Gene name: frizzled-related protein
Probe: Frzb probe
Probe preparation: Antisense RNA
Results
Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cochlea epithelium Present Regionally restricted 4A Expression was detected in the prosensory epithelium.

Specimen 4B: embryonic day 15.5 (more )
Note: Base
Structure Level Pattern Image Note
TS23: lesser epithelial ridge Present 4B

Specimen 4C: embryonic day 17.5 (more )
Note: Base
Structure Cell Type Level Pattern Image Note
TS25: lesser epithelial ridge Present 4C
TS25: cochlea cochlear outer hair cell Present 4C
TS25: cochlea Deiter's cell Present 4C

Specimen 4D: postnatal day 0 (more )
Note: Base
Structure Cell Type Level Pattern Image Note
TS27: cochlea cochlear outer hair cell Present 4D
TS27: cochlea Deiter's cell Present 4D
TS27: cochlea epithelium Present Non-Uniform 4D Expression was higher in the sensory epithelium than in the lesser epithelial ridge in the base at P0.
TS27: lesser epithelial ridge Present 4D

Specimen 4D inset: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: cochlea external pillar cell of cochlea Present 4D inset
TS27: cochlea Deiter's cell Present Regionally restricted 4D inset Expression was detected in the first and second Deiter's cells but not in the third Deiter's cell.
TS27: cochlea internal pillar cell of cochlea Absent 4D inset

Specimen 4E: postnatal day 4 (more )
Note: Apex
Structure Cell Type Level Pattern Image Note
TS28: cochlea Claudius cell Present 4E
TS28: cochlea cochlear outer hair cell Present 4E
TS28: cochlea epithelium Present Non-Uniform 4E Expression in the sensory epithelium persisted in the apical turn. Expression was far higher in the lesser epithelial ridge than in the sensory epithelium at P4.
TS28: lesser epithelial ridge Present 4E

Specimen 4F: postnatal day 6 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea Claudius cell Present 4F
TS28: internal spiral sulcus Strong 4F
TS28: lesser epithelial ridge Strong 4F
TS28: cochlea epithelium Strong Regionally restricted 4F Expression was strong in the lesser epithelial ridge, but was absent in the sensory epithelium.

Specimen 4G: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea Claudius cell Present 4G
TS28: internal spiral sulcus Strong 4G
TS28: lesser epithelial ridge Strong 4G
TS28: cochlea epithelium Strong Regionally restricted 4G Expression was strong in the lesser epithelial ridge, but was absent in the sensory epithelium.

Specimen 4I: postnatal day 0 (more )
Note: Apex
Structure Level Pattern Image Note
TS27: cochlea epithelium Present Regionally restricted 4J , 4I Expression was detected in the sensory epithelium and the lesser epithelial ridge. Expression was reciprocal to Wnt5a expression in the greater epithelial ridge.
TS27: lesser epithelial ridge Present 4J , 4I


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory