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Gene Expression Data
Assay Details
Assay
Reference: J:253527 Geng R, et al., Comprehensive Expression of Wnt Signaling Pathway Genes during Development and Maturation of the Mouse Cochlea. PLoS One. 2016;11(2):e0148339
Assay type: RNA in situ
MGI Accession ID: MGI:7526741
Gene symbol: Sfrp1
Gene name: secreted frizzled-related protein 1
Probe: Sfrp1 cDNA
Probe preparation: Antisense RNA
Results
Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cochlea epithelium Present Regionally restricted 3A Expression was detected in the prosensory epithelium.
TS20: cochlea Present Widespread 3A
Specimen 3B: postnatal day 0 (more )
Note: Basal turn of the cochlea.
Structure Cell Type Level Pattern Image Note
TS27: greater epithelial ridge Present Regionally restricted 3B
TS27: lesser epithelial ridge Present Regionally restricted 3B
TS27: cochlea cochlea auditory hair cell Present 3B
TS27: cochlea supporting cell of cochlea Present 3B
TS27: cochlear duct Present Regionally restricted 3B Expression was localized to the luminal surface of the floor of the cochlear duct.
Specimen 3C: postnatal day 6 (more )
Note: Apex
Structure Cell Type Level Pattern Image Note
TS28: greater epithelial ridge Present 3C
TS28: cochlea epithelium Present Regionally restricted 3C Expression was in the greater and lesser epithelial ridge.
TS28: cochlea supporting cell of cochlea Present Regionally restricted 3C Expression remained in the supporting cells in the apical turn.
TS28: cochlea cochlea auditory hair cell Absent 3C
TS28: cochlear duct Present Regionally restricted 3C Expression remained throughout the floor of the duct.
Specimen 3D: postnatal day 6 (more )
Note: Mid
Structure Cell Type Level Pattern Image Note
TS28: greater epithelial ridge Present 3D
TS28: cochlea epithelium Present Regionally restricted 3D Expression was in the greater and lesser epithelial ridge.
TS28: cochlea supporting cell of cochlea Present Regionally restricted 3D Expression remained in the supporting cells in the mid basal turn.
TS28: cochlea cochlea auditory hair cell Absent 3D
TS28: cochlear duct Present Regionally restricted 3D Expression remained throughout the floor of the duct.
Specimen 3E: postnatal day 6 (more )
Note: Base
Structure Cell Type Level Pattern Image Note
TS28: greater epithelial ridge Present 3E
TS28: cochlea epithelium Present Regionally restricted 3E Expression was in the greater epithelial ridge, but was downregulated in the lesser epithelial ridge.
TS28: cochlea cochlea auditory hair cell Absent 3E
TS28: cochlea supporting cell of cochlea Absent 3E
Specimen 3F: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cochlea Absent 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory