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Gene Expression Data
Assay Details
Assay
Reference: J:140027 Zou D, et al., Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. Hum Mol Genet. 2008 Nov 1;17(21):3340-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526727
Gene symbol: Cdkn1b
Gene name: cyclin dependent kinase inhibitor 1B
Antibody: anti-p27Kip1
Results
Specimen 5A: embryonic day 14.0; Eya1bor/Eya1+ (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 5A Expressed in the prosensory domain.
Specimen 5B: embryonic day 14.0; Eya1tm1Rilm/Eya1+ (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 5B Expressed in the prosensory domain.
Specimen 5C: embryonic day 14.0; Eya1bor/Eya1bor (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Diffuse 5C Expression domain appeared to be diffused and not as sharply defined as in controls.
Specimen 5J: embryonic day 18.5; Eya1bor/Eya1+ (more )
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti supporting cell of cochlea Present 5J
TS26: greater epithelial ridge border cell of cochlea Present 5J
Specimen 5K: embryonic day 18.5; Eya1tm1Rilm/Eya1+ (more )
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti supporting cell of cochlea Present 5K Expression pattern was not altered, although the cochlea epithelium appears to be thinner.
TS26: greater epithelial ridge border cell of cochlea Present 5K
Specimen 5L: embryonic day 18.5; Eya1bor/Eya1bor (more )
Structure Level Pattern Image Note
TS26: organ of Corti Weak 5L Weak and disorganized expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory