Reporter:	lacZ
	Direct Detection

Structure	Level	Pattern	Image	Note
TS21: semicircular canal epithelium	Present		4A	Expressed throughout the thickness of the epithelia, showed overlapping pattern with Sox2.

Structure	Level	Pattern	Image	Note
TS21: utricle epithelium	Present		4B	Expressed throughout the thickness of the epithelia, showed overlapping pattern with Sox2.

Structure	Cell Type	Level	Pattern	Image	Note
TS23: vestibular component epithelium	vestibular hair cell	Present		4D	Expression became progressively restricted to the differentiating hair cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: saccule epithelium	vestibular hair cell	Present		4E	Expression became progressively restricted to the differentiating hair cells.

Structure	Level	Pattern	Image	Note
TS21: cochlea epithelium	Present	Regionally restricted	4F	In the more mature basal regions, expressed in the future organ of Corti, but its expression extended into the entire epithelium in the great epithelial ridge.

Structure	Level	Pattern	Image	Note
TS22: cochlea epithelium	Present	Regionally restricted	4H	Expression gradually disappeared in the border cells in the great epithelial ridge adjacent to the future organ of Corti, where the level of Sox2 distribution was gradually increased. Expression remained in the epithelial cells that will give rise to the inner sulcus cells where Sox2 is not expressed.

Structure	Level	Pattern	Image	Note
TS22: cochlea epithelium	Present	Regionally restricted	4L	Expression gradually disappeared in the border cells in the great epithelial ridge adjacent to the future organ of Corti, where the level of Sox2 distribution was gradually increased. Expression remained in the epithelial cells that will give rise to the inner sulcus cells where Sox2 is not expressed.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: greater epithelial ridge		Present	Regionally restricted	4N	Expression gradually disappeared in the border cells in the great epithelial ridge adjacent to the future organ of Corti, where the level of Sox2 distribution was gradually increased. Expression remained in the epithelial cells that will give rise to the inner sulcus cells where Sox2 is not expressed.
TS24: organ of Corti	cochlea auditory hair cell	Strong		4N
TS24: organ of Corti	supporting cell of cochlea	Trace		4N	Almost completely disappeared in the supporting cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: organ of Corti	cochlea auditory hair cell	Strong		4P
TS27: greater epithelial ridge		Absent		4P	Very faint and became undetectable on sections.
TS27: cochlea epithelium		Present	Regionally restricted	4P	Expressed in the epithelial cells outside of the great epithelial ridge.

Structure	Level	Pattern	Image	Note
TS15: otocyst	Present	Regionally restricted	6M	Restricted to the ventral wall.

Structure	Level	Pattern	Image	Note
TS21: cochlea epithelium	Present			Expressed in a broad group of cells in the less mature apical region throughout the thickness of the epithelium including the site of the future organ of Corti, and overlapped with Sox2 domain.