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Gene Expression Data
Assay Details
Assay
Reference: J:181471 Ahmed M, et al., Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7526436
Gene symbol: Eya1
Gene name: EYA transcriptional coactivator and phosphatase 1
Reporter: lacZ
Direct Detection
Results
Specimen 1D E13.5 apical: embryonic day 13.5; Eya1tm1Px/Eya1+ (more )
Structure Level Pattern Image Note
TS21: cochlea epithelium Present 1D E13.5 apical Expression was observed in a broad group of cells throughout the thickness of the epithelium including the site of the future organ of Corti.

Specimen 1D E13.5 basal: embryonic day 13.5; Eya1tm1Px/Eya1+ (more )
Structure Level Pattern Image Note
TS21: cochlea epithelium Present Regionally restricted 1D E13.5 basal Expression was observed in a broad group of cells throughout the thickness of the epithelium including the site of the future organ of Corti.

Specimen 1D E14.5 apical: embryonic day 14.5; Eya1tm1Px/Eya1+ (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 1D E14.5 apical Expression was observed in a broad group of cells throughout the thickness of the epithelium including the site of the future organ of Corti.

Specimen 1D E14.5 mid-basal: embryonic day 14.5; Eya1tm1Px/Eya1+ (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 1D E14.5 mid-basal

Specimen 1D E15.5 apical: embryonic day 15.5; Eya1tm1Px/Eya1+ (more )
Structure Level Pattern Image Note
TS23: cochlea epithelium Strong Regionally restricted 1D E15.5 Expression became abundantly distributed in differentiating hair cells.

Specimen 1D E16.5 basal: embryonic day 16.5; Eya1tm1Px/Eya1+ (more )
Structure Cell Type Level Pattern Image Note
TS24: organ of Corti cochlear inner hair cell Strong 1D E16.5
TS24: organ of Corti cochlear outer hair cell Strong 1D E16.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory