Gene Expression Data
Assay Details
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Assay
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Reference:
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J:181471
Ahmed M, et al., Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7526433
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Gene symbol:
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Six1
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Gene name:
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sine oculis-related homeobox 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1B E13.25:
embryonic day 13.25; Six1tm1Mair/Six1 +
(more  )
Specimen
1B E13.25:
(close  )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 13.25
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cochlea epithelium |
Present |
Regionally restricted |
1B E13.25
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Expression disappeared in the postmitotic progenitors within the prosensory domain.
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Specimen
1B E13.5 basal:
embryonic day 13.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E13.5 basal:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cochlea epithelium |
Present |
Regionally restricted |
1B E13.5 basal
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Expression was only observed in a single column of cells at the medial border of the prosensory domain near the basal cochlea duct where inner hair cells will appear, but not in the apical or medial regions.
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Specimen
1B E13.5 apical:
embryonic day 13.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E13.5 apical:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cochlea epithelium |
Present |
Regionally restricted |
1B E13.5 apical
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Expression was only observed in a single column of cells at the medial border of the prosensory domain near the basal cochlea duct where inner hair cells will appear, but not in the apical or medial regions.
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Specimen
1B E13.5 WM:
embryonic day 13.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E13.5 WM:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cochlea epithelium |
Present |
Regionally restricted |
1B E13.5 WM
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Expression was only observed in a single column of cells at the medial border of the prosensory domain near the basal cochlea duct where inner hair cells will appear, but not in the apical or medial regions.
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Specimen
1B E14.5 basal:
embryonic day 14.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E14.5 basal:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cochlea epithelium |
Present |
Regionally restricted |
1B E14.5 basal
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Expressed in the medial border of the prosensory domain where inner hair cells develop near the basal cochlea duct. Also expressed in a second column where innermost outer hair cells appear.
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Specimen
1B E14.5 apical:
embryonic day 14.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E14.5 apical:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cochlea epithelium |
Present |
Regionally restricted |
1B E14.5 apical
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Expressed in the medial border of the prosensory domain where inner hair cells develop near the basal cochlea duct.
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Specimen
1B E14.5 WM:
embryonic day 14.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E14.5 WM:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cochlea epithelium |
Present |
Regionally restricted |
1B E14.5 WM
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Expression domain extended toward the apex, but its expression was not observed in the apical end.
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Specimen
1B E15.5 mid-basal:
embryonic day 15.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E15.5 mid-basal:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1B E15.5 apical:
embryonic day 15.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E15.5 apical:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cochlea epithelium |
Present |
Regionally restricted |
1B E15.5 apical
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Expressed in the medial border of the prosensory domain where inner hair cells develop near the basal cochlea duct. Also expressed in a second column where innermost outer hair cells appear.
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Specimen
1B E16.5 basal:
embryonic day 16.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E16.5 basal:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1B E16.5 apical:
embryonic day 16.5; Six1tm1Mair/Six1 +
(more )
Specimen
1B E16.5 apical:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Six1tm1Mair/Six1+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: cochlea epithelium |
Present |
Regionally restricted |
1B E16.5 apical
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Expressed in the medial border of the prosensory domain where inner hair cells develop near the basal cochlea duct. Also expressed in a second column where innermost outer hair cells appear.
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Analysis Tools
