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Gene Expression Data
Assay Details
Assay
Reference: J:181471 Ahmed M, et al., Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526431
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1A E13.25: embryonic day 13.25 (more )
Structure Level Pattern Image Note
TS21: cochlea epithelium Strong Regionally restricted 1A E13.25 Expressed strongly in the postmitotic progenitors in the prosensory domain. Also expressed in the greater epithelial ridge.
Specimen 1A E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cochlea epithelium Strong Regionally restricted 1A E13.5 Expressed strongly in the postmitotic progenitors in the prosensory domain. Also expressed in the greater epithelial ridge.
Specimen 1A E14.5 apical: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Strong Regionally restricted 1A E14.5 apical Expressed strongly in the postmitotic progenitors in the prosensory domain. Also expressed in the greater epithelial ridge.
Specimen 1A E14.5 mid-basal: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Strong Regionally restricted 1A E14.5 mid-basal Expressed strongly in the postmitotic progenitors in the prosensory domain. Also expressed in the greater epithelial ridge.
Specimen 1A E15.5: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: cochlea epithelium cochlea auditory hair cell Present 1A E15.5 Expression was downregulated in nascent hair cells and disappears in more mature hair cells.
Specimen 1A E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Regionally restricted 1A E16.5 Expression was downregulated in nascent hair cells and disappears in more mature hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory