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Gene Expression Data
Assay Details
Assay
Reference: J:132979 Potok MA, et al., WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526040
Gene symbol: Cga
Gene name: glycoprotein hormones, alpha subunit
Antibody: anti-alphaGSU
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2E: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: adenohypophysis gonadtroph Present 2E
TS24: adenohypophysis thyrotroph Present 2E

Specimen 2F: embryonic day 16.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Cell Type Level Pattern Image Note
TS24: adenohypophysis gonadtroph Present 2F Expression unchanged compared to wild-type.
TS24: adenohypophysis thyrotroph Present 2F Expression unchanged compared to wild-type.

Specimen 2G: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: adenohypophysis gonadtroph Present 2G
TS26: adenohypophysis thyrotroph Present 2G

Specimen 2H: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Cell Type Level Pattern Image Note
TS26: adenohypophysis gonadtroph Present 2H Expression unchanged compared to wild-type.
TS26: adenohypophysis thyrotroph Present 2H Expression unchanged compared to wild-type.

Specimen 4Bm: embryonic day 18.5; Wnt4tm1Amc/Wnt4+, Wnt5atm1Amc/Wnt5a+ (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 4Bm

Specimen 4Bn: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 4Bn

Specimen 4Bo: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 4Bo

Specimen 4Bp: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc, Wnt5atm1Amc/Wnt5atm1Amc (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 4Bp Expression not drastically reduced.

Specimen 5 alphaGSU +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 5_alphaGSU +/+

Specimen 5 alphaGSU -/-: embryonic day 18.5; Wnt6tm1Akis/Wnt6tm1Akis (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 5_alphaGSU -/- Expression unchanged compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory