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Gene Expression Data
Assay Details
Assay
Reference: J:195951 Kurogane Y, et al., FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells. Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):988-96
Assay type: RNA in situ
MGI Accession ID: MGI:7524596
Gene symbol: Fgd5
Gene name: FYVE, RhoGEF and PH domain containing 5
Probe: Fgd5 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D: embryonic day 10.0 (more )
Structure Cell Type Level Pattern Image Note
TS16: embryo endothelial cell Present Widespread 1D Expression in all endothelial cells.
Specimen 1E: embryonic day 10.0 (more )
Structure Cell Type Level Pattern Image Note
TS16: head blood vessel blood vessel endothelial cell Present 1E Expression in endothelial cells in large vessels.
TS16: future brain endothelial cell of vascular tree Present Regionally restricted 1E Expression in endothelial cells in capillary plexus around developing brain.
Specimen 1F: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: dorsal aorta Present 1F
TS16: intersomitic blood vessel Present 1F
Specimen 1G P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: retina blood vessel Strong Regionally restricted 1G FGD5 P4 Strong expression in retinal vasculature at postnatal day 4. Expression predominantly detected in capillaries and veins, particularly at advancing vascular fronts.
Specimen 1G P8: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: retina blood vessel Ambiguous Regionally restricted 1G FGD5 P8 Expression dowregulated in preformed vessels at postnatal day 8.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory