Gene Expression Data
Assay Details
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Assay
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Reference:
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J:167050
Khan QE, et al., Expression of prion gene and presence of prion protein during development of mouse molar tooth germ. Eur J Oral Sci. 2010 Dec;118(6):559-65
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7524405
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Gene symbol:
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Prnp
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Gene name:
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prion protein
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Results
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Specimen
3:
embryonic day 18.5
(more  )
Specimen
3:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
4A:
embryonic day 18.5
(more )
Specimen
4A:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: lower jaw molar |
ameloblast |
Present |
Regionally restricted |
4A
,
4B
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Marked staining is seen in the distal part of ameloblasts approaching the secretory stage on the distal cusp aspect, and absent in ameloblasts on the mesial aspect . Immunolabelling is observed in the ameloblast body close to the cusp tip.
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| TS26: lower jaw molar dental papilla |
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Present |
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4A
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4B
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| TS26: lower jaw molar enamel organ |
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Present |
Regionally restricted |
4A
,
4B
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Outer enamel epithelium showed distinct immunolabelling. Inner enamel epithelium was weakly labeled.
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| TS26: eye |
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Present |
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4A
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Specimen
4C:
embryonic day 18.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: lower jaw molar |
ameloblast |
Strong |
Regionally restricted |
4C
,
4D
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Strong immunolabelling is visible in ameloblasts at the cusp tip, in the cervical loop, and in the outer enamel epithelium, but is absent in ameloblasts that have not reached the secretory stage. Immunolabeling was also evident in ameloblasts in general.
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| TS26: lower jaw molar dental papilla |
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Present |
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4D
,
4C
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| TS26: cervical loop |
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Strong |
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4C
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4D
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| TS26: lower jaw molar enamel organ |
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Present |
Regionally restricted |
4D
,
4C
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Outer enamel epithelium showed distinct immunolabelling. Inner enamel epithelium was weakly labeled.
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Specimen
5A:
embryonic day 18.5
(more )
Note: Transverse section of the incisor in
the apical part (early developmental stage).
Specimen
5A:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Note:
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Transverse section of the incisor in
the apical part (early developmental stage).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: incisor enamel organ |
Present |
Regionally restricted |
5A
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Expression was detected in the outer enamel epithelium. Some immunolabelling was also evident in the inner enamel epithelium.
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| TS26: cervical loop |
Strong |
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5A
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| TS26: incisor dental papilla |
Present |
Regionally restricted |
5A
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Expression was detected in central peripheral parts of the dental papilla.
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Specimen
5B:
embryonic day 18.5
(more )
Note: Transverse section of the incisor in
the incisal part (later developmental stage).
Specimen
5B:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Note:
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Transverse section of the incisor in
the incisal part (later developmental stage).
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: incisor enamel organ |
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Strong |
Regionally restricted |
5B
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Strong expression was detected in the outer enamel epithelium.
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| TS26: incisor |
ameloblast |
Present |
Regionally restricted |
5B
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Ameloblasts entering the secretory stage also stained positive.
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| TS26: incisor dental papilla |
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Present |
Regionally restricted |
5B
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Expression was detected in the central part of the dental papilla.
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Specimen
6A:
embryonic day 18.5
(more )
Specimen
6A:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
S2b:
embryonic day 18.5
(more )
Specimen
S2b:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: brain |
Present |
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S2b
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Specimen
S2c:
embryonic day 18.5
(more )
Specimen
S2c:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: liver |
Absent |
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S2c
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