Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Asb4em1(cre/ERT2)Awx
Name:	ankyrin repeat and SOCS box-containing 4; endonuclease-mediated mutation 1, Allison W Xu
MGI ID:	MGI:7522997
Synonyms:	Asb4t2aCreERt2
Gene:	Asb4  Location: Chr6:5383386-5433022 bp, + strand  Genetic Position: Chr6, 1.99 cM
Alliance:	Asb4em1(cre/ERT2)Awx page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Asb4em1(cre/ERT2)Awx expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Asb4 (MGI:1929751)   Mutation details: The t2a-CreERT2 cassette was inserted into the Asb4 locus to replace the STOP codon with CRISPR technology. (J:339272)

Activity:	Tissue activity of this recombinase allele
Driver:	Asb4 (mouse) Summary of all recombinase alleles driven by Asb4. Comparative matrix view of recombinase activities Alliance mouse Asb4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asb4 Mutation:	30 strains or lines available

Original:	J:339272 Vagena E, et al., ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis. Sci Signal. 2022 May 10;15(733):eabj8204
All:	1 reference(s)