About   Help   FAQ
Tg(COL2A1-SV40T)#Ksec
Transgene Detail
Summary
Symbol: Tg(COL2A1-SV40T)#Ksec
Name: transgene insertion, Kathryn S E Cheah
MGI ID: MGI:2445588
Transgene: Tg(COL2A1-SV40T)#Ksec  Location: unknown  
Alliance: Tg(COL2A1-SV40T)#Ksec page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA/CaHN)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene consists of the human COL2A1 promoter (the first ~4.5 kb upstream of transcription site), SV40 T antigen gene and COL2A1 intron 1. The promoter was used to drive expression of the transgene in differentiating chondrocytes. (J:80223)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:80223 Cheah KS, et al., Human COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development. J Cell Biol. 1995 Jan;128(1-2):223-37
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory