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Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7522381
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1 (AB31940)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen S10C Dmrt5+/+: embryonic day 18.5 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:7522382).
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted S10C Tbr1 Dmrt5+/+ , S10C Merge right Dmrt5+/+ Layer-VI marker.
TS26: cortical subplate Present S10C Merge right Dmrt5+/+ , S10C Tbr1 Dmrt5+/+
Specimen S10C Dmrt5-/-: embryonic day 18.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:7522382).
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted S10C Merge right Dmrt5-/- , S10C Tbr1 Dmrt5-/- Expression in the mutant neocortex layers was confirmed with a more diffuse distribution.
TS26: cortical subplate Present S10C Tbr1 Dmrt5-/- , S10C Merge right Dmrt5-/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory