About   Help   FAQ
Tg(COL2A1-lacZ)KL80.3Ksec
Transgene Detail
Summary
Symbol: Tg(COL2A1-lacZ)KL80.3Ksec
Name: transgene insertion KL80.3, Kathryn S E Cheah
MGI ID: MGI:7522371
Synonyms: COL2A1/lacZ
Transgene: Tg(COL2A1-lacZ)KL80.3Ksec  Location: unknown  
Alliance: Tg(COL2A1-lacZ)KL80.3Ksec page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA/CaHN)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene insert contains the following elements: human COL2A1 promoter (first 6.1 kb upstream of transcription start site), exon 1, bp 2388-2696 of intron 1 and the beta-galactosidase reporter gene. The intron 1 sequence contains Sox9-binding enhancers. (J:41294)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:41294 Bell DM, et al., SOX9 directly regulates the type-II collagen gene [see comments]. Nat Genet. 1997 Jun;16(2):174-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory